Nefrosave forte tablet consists of the active substances N-acetylcysteine 300mg and pyridoxamine dihydrochloride 50mg. It is used in the management of diabetic nephropathy and as an antidote for paracetamol poisoning. Diabetic nephropathy is a crucial factor leading to end-stage kidney disease. It is a result of various factors such as poor glycaemic control, prolonged diabetes, hypertension, family history, and other complications. This medicine protects the kidney from injury caused by contrast media, ischemia and toxins. It also detoxifies the body from the effects of over-dosage of paracetamol. Individuals with allergic reactions to the ingredients and severe infections should consult their doctor before taking the nefrosave forte tablet . Talk to your doctor immediately if you have any allergic reaction (difficulty with breathing, chest tightness rash, itching, hives, swelling lips, tongue, or face), infection (short- or long-term), tuberculosis, intestinal ulcers or diverticulitis (small bulging pouches developed in the digestive tract), liver disease, cancer, kidney function problems, and persistent headaches. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding.