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Kynteles 300mg Injection
Manufacturer/Marketed By : TAKEDA PHARMACEUTICALS INDIA PVT LTD
$711.88 $638.49
Kynteles 300mg injection contains the active component of vedolizumab, which belongs to the group of biological medicines known as monoclonal antibodies (MAbs). It is used as a treatment option for...
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VEDOLIZUMAB
Active Pharmaceutical Ingredient
Kynteles 300mg Injection
711,88$
638,49$
Kynteles 300mg injection contains the active component of vedolizumab, which belongs to the group of biological medicines known as monoclonal antibodies (MAbs). It is used as a treatment option for adults dealing with moderate to severe cases of ulcerative colitis (inflammation of the large bowel), Crohn's disease (inflammation affecting the digestive system), and chronic pouchitis (inflammation of the lining of a pouch created during surgery to treat ulcerative colitis). In these three conditions, your initial course of treatment will typically involve other medications. If you do not respond well to them or experience intolerable side effects, your doctor may prescribe Kynteles 300mg injection to help alleviate the signs and symptoms of your condition. Do not take this medication if you are under 18 or have allergies to vedolizumab or its components. Additionally, it is essential to inform your doctor if you have an active severe infection, such as tuberculosis (TB), blood poisoning, severe diarrhoea and vomiting (gastroenteritis), or nervous system infection. Another critical point is that you should not take this medication with other biological medicines that suppress your immune system, such as natalizumab or rituximab. Inform your healthcare provider if you plan to receive a vaccination or have recently had one. Vedolizumab may impact your response to vaccines. Always provide your doctor with a comprehensive overview of your medical history and the medications you are taking before starting this treatment. If you experience any possible side effects during or after treatment, don't hesitate to notify your doctor promptly.
Active Pharmaceutical Ingredient
Uses
• Ulcerative colitis
• Crohn's disease
• Chronic pouchitis
Benefits
The primary mechanism of action of vedolizumab is to inhibit the activity of a protein on the surfaces of white blood cells, which is responsible for the inflammation associated with ulcerative colitis, Crohn's disease, and pouchitis — this inhibition of the protein results in a decrease in the amount of inflammation.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Most Common Side Effects
• Common cold, fever, and night sweats
• Pain in joint, back, throat, or limb
• Headache and tiredness
• Infections
• Muscle cramps and weakness
• Bloated stomach
• High blood pressure
• Heartburn
• Haemorrhoids
• Eczema and acne (pimples)
Common Side Effects
• Allergic reactions - the signs may include wheezing or difficulty breathing, hives, itching of the skin, swelling, feeling sick, pain at the infusion site, redness of skin
• Serious infections - the signs may include chills, shivering, high fever, or rash.
• Progressive Multifocal Leukoencephalopathy - PML (a rare fatal opportunistic infection of the central nervous system)
• Severe liver injury
How To Use
This medicine is given only in a hospital setup by a healthcare provider. It is infused directly into your veins by your physician. Your physician will decide the dosage, frequency, and schedule of the course of treatment based on the severity of your disorder and other factors. Do not miss or skip any scheduled dose. Do not stop the treatment without the doctor's acknowledgment.
Safety Advice
• Breast Feeding: It is important to let your doctor know if you are breastfeeding or planning to breastfeed because studies suggest that kynteles 300mg injection can pass into breast milk. Your doctor will decide whether to prescribe this medication after carefully weighing the benefits against the risks to your baby.
• Alcohol: Generally, it is recommended to avoid alcohol consumption during the treatment with kynteles 300mg injection as it can cause significant liver injury. Please consult your doctor for more advice.
• Liver: Kynteles 300mg injection can cause significant liver injury that may lead to fatal or the need for liver transplant in some patients. Hence, do not take this injection if you have a severe liver disorder or jaundice. Inform your doctor if you have any liver disease before starting the treatment.
• Lungs: It is unknown whether kynteles 300mg injection is safe for patients suffering from lung disease. Inform your doctor if you have any lung disease before starting the treatment.
• Driving: Kynteles 300mg injection can cause mild dizziness during the treatment. If you feel dizzy, do not drive or use heavy machines. Check with your doctor for more advice.
• Pregnancy: It is unknown whether this medicine is safe during pregnancy. Therefore, it is given when the benefit for the mother outweighs the risk to the foetus. Tell your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant before taking this medication.
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