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Anvimo 480mg Tablet
Manufacturer/Marketed By : ZYDUS CADILA
$329.39 $303.05
Anvimo 480mg Tablet is an Anti-Viral medication containing letermovir as its active ingredient. It belongs to the pharmacological class of Anti-Viral agents and is specifically classified under cytomegalovirus (CMV) DNA...
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LETERMOVIR
Active Pharmaceutical Ingredient
Anvimo 480mg Tablet
329,39 $US
303,05 $US
Anvimo 480mg Tablet is an Anti-Viral medication containing letermovir as its active ingredient. It belongs to the pharmacological class of Anti-Viral agents and is specifically classified under cytomegalovirus (CMV) DNA terminase inhibitors. Anvimo 480mg Tablet is primarily used to prevent cytomegalovirus (CMV) infection in patients who have recently undergone an allogeneic hematopoietic stem cell transplant (HSCT) and are at a higher risk of CMV reactivation. Anvimo 480mg Tablet works by inhibiting the CMV DNA terminase complex, which is crucial for viral replication. It is typically prescribed for CMV-seropositive adult patients post-transplant to reduce the likelihood of viral complications. However, the medication is not a treatment for existing CMV infections. Patients taking this medication should follow strict safety precautions. It is contraindicated in individuals with known hypersensitivity to letermovir or any of its excipients. Additionally, it is not recommended for use with certain medications due to serious drug interactions. Healthcare professionals advise caution in pregnant or breastfeeding women, individuals with liver impairment, and those consuming alcohol.
Active Pharmaceutical Ingredient
Uses
• Have undergone allogeneic hematopoietic stem cell transplantation (HSCT)
• Are CMV-seropositive, meaning they have previously been exposed to the virus
Benefits
Anvimo 480mg Tablet functions by blocking the CMV DNA terminase complex, a key component required for viral replication. Unlike conventional antiviral drugs that target DNA polymerase, this medication disrupts viral DNA processing and packaging, ultimately preventing the virus from multiplying and spreading in the body.
Side Effects
Common Side Effects:
Most Common Side Effects
• Irregular heartbeat
• Swelling in legs or feet
• Unexplained bleeding or bruising
• Severe allergic reactions (rash, breathing difficulty)
Common Side Effects
• Nausea
• Fatigue
• Headache
• Diarrhea
• Abdominal pain
How To Use
The usual recommended dosage of Anvimo 480mg Tablet for CMV prophylaxis is 480 mg once daily. However, if taken in combination with cyclosporine, the dose is reduced to 240 mg daily to prevent excessive drug levels. This medication is available in oral tablets and intravenous (IV) infusion forms. Oral tablets should be swallowed whole with or without food, while the IV infusion must be administered under medical supervision to ensure proper dosing and monitoring.
Safety Advice
• Breast Feeding: It is unknown whether Anvimo 480mg Tablet passes into breast milk. A healthcare provider should assess whether to discontinue breastfeeding or the medication.
• Alcohol: Alcohol can increase liver toxicity and should be avoided during treatment.
• Liver: Patients with severe liver impairment should use caution, as Anvimo 480mg Tablet is metabolised in the liver. Dose adjustments may be required.
• Lungs: No major respiratory effects have been reported. Patients with existing lung conditions can take Anvimo 480mg Tablet under medical guidance.
• Driving: Anvimo 480mg Tablet does not impair alertness or cognitive function. Patients can safely drive and operate machinery unless experiencing dizziness.
• Pregnancy: There is limited human data on Anvimo 480mg Tablet during pregnancy. It should only be used if the benefits outweigh the potential risks to the fetus.
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