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Zemdri Injection
Manufacturer/Marketed By : CIPLA LTD
$147.75 $125.79
Zemdri Injection is an advanced aminoglycoside antibiotic used for treating serious bacterial infections. It contains the active molecule Plazomicin, which is primarily indicated for the treatment of complicated urinary tract...
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PLAZOMICIN
Active Pharmaceutical Ingredient
Zemdri Injection
147,75$
125,79$
Zemdri Injection is an advanced aminoglycoside antibiotic used for treating serious bacterial infections. It contains the active molecule Plazomicin, which is primarily indicated for the treatment of complicated urinary tract infections (cUTIs), including pyelonephritis, caused by certain multidrug-resistant (MDR) gram-negative bacteria. It may also be used in other off-label resistant infections under expert medical supervision. Inform your physician if you have a history of kidney problems, hearing loss, or neurological disorders. Do not take this medicine if you are allergic to Plazomicin or other aminoglycosides. Your doctor will monitor kidney function and drug levels during treatment.
Active Pharmaceutical Ingredient
Uses
• Treatment of complicated urinary tract infections (cUTIs), including pyelonephritis
• May be used in certain multidrug-resistant gram-negative infections when other antibiotics are ineffective
Benefits
Zemdri Injection exerts its antibacterial effect by binding to bacterial 30S ribosomal subunits, inhibiting protein synthesis, and ultimately leading to cell death. It is bactericidal in nature and effective against pathogens resistant to other aminoglycosides due to its structural modification, which helps evade inactivating enzymes.
Side Effects
Common side effects:
Most Common Side Effects
• Kidney damage (nephrotoxicity)
• Hearing loss or ringing in the ears (ototoxicity)
• Balance issues or vertigo
• Allergic reactions such as swelling, rash, or trouble breathing
Common Side Effects
• Nausea
• Diarrhea
• Headache
• Dizziness
• Increased creatinine levels (a marker of kidney function)
How To Use
Zemdri Injection is administered via intravenous infusion over 30 minutes, typically once daily. It should only be given by a qualified healthcare professional in a clinical setting. Do not self-administer.
Safety Advice
• Breast Feeding: It is unknown whether Plazomicin is excreted in human milk. Caution is advised; consult your doctor before breastfeeding during treatment.
• Alcohol: Avoid consuming alcohol during treatment as it may worsen dizziness or increase kidney-related side effects.
• Liver: No dose adjustment is typically required for hepatic impairment, but inform your physician of any liver conditions.
• Lungs: There are no specific concerns regarding lung impairment, but inform your doctor if you have respiratory issues.
• Driving: Avoid driving or using heavy machinery if you feel lightheaded, dizzy, or tired during treatment.
• Pregnancy: Zemdri Injection should only be used during pregnancy if absolutely necessary. It may pose a risk of fetal harm. Discuss risks vs benefits with your physician.
Disclaimer
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