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Knilonat 150mg Capsule
Manufacturer/Marketed By : NATCO PHARMA LTD
$8.89 $7.11
Knilonat 150mg capsule is an antineoplastic drug with an active ingredient called Nilotinib. It belongs to the medication class known as tyrosine kinase inhibitors. This medicine is used to treat...
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NILOTINIB
Active Pharmaceutical Ingredient
Knilonat 150mg Capsule
8.89$
7.11$
Knilonat 150mg capsule is an antineoplastic drug with an active ingredient called Nilotinib. It belongs to the medication class known as tyrosine kinase inhibitors. This medicine is used to treat a type of leukemia called Philadelphia chromosome-positive chronic myeloid leukemia (Ph-positive CML), a blood cancer with abnormal production of WBC. In adult and pediatric patients, it is used in a patient who is newly diagnosed with Chronic Myeloid Leukemia (CML) and those facing side effects from previous treatment. Additionally, it is also used in patients with no longer respond to the previous treatment including Imatinib. Do not take this medicine if you are allergic to Nilotinib or the other ingredients of this medicine. Notify your doctor if you have or had a history of heart conditions (heart attack, abnormal electric signal), chest pain, brain stroke, or claudication ( condition of blood flow in the leg). Inform your doctor if you have liver or pancreas disorder, or suffering from a lack of potassium or magnesium. You need to tell your doctor about all the medications especially if you take medicine to lower your blood cholesterol. Tell your doctor about your underlying condition especially inform about if you have or ever had a hepatitis B infection; this medicine can activate HPV again which can be fatal in some cases. Avoid consuming grapefruit or grapefruit juice. Inform your doctor if you are intolerant to some sugar, as this medicine contains lactose. During the treatment, your doctor may conduct a regular blood test to monitor the liver and pancreas function, and the number of blood cells (WBC, RBC, platelets). Also to monitor the heart condition (prolongation of the QT interval), electrolytes in the body, and the level of sugar and fats to check how Knilonat 150mg capsule is tolerated. Inform your doctor if you are pregnant or planning to get pregnant or breastfeeding. Use effective birth control during the treatment with this medicine.
Active Pharmaceutical Ingredient
Uses
• Blood cancer (Philadelphia chromosome-positive chronic myeloid leukemia) in adults and pediatrics.
Benefits
BCR-ABL tyrosine kinase is responsible for the uncontrolled division of cells in the CML. Knilonat 150mg capsule disrupts the signaling route of the protein kinase enzyme which targets the BCR-ABL protein and inhibits the growth and spread of cancer cells.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Most Common Side Effects
• Nausea, vomiting, diarrhoea.
• Headache, muscle pain, stomach pain.
• Hair loss.
• Tiredness.
• Constipation.
• Slowing growth in children.
• Pneumonia.
• Loss of appetite.
• Sleeplessness, depression, and anxiety.
• Stomach discomforts like bloating and flatulence after meals.
• musculoskeletal pain
Common Side Effects
• Sudden weight gain
• Swelling in hands, feet, ankles, or face
• Chest pain
• Blood pressure (high and low)
• Discoloration of tongue, lips, or skin (blue)
• Abnormal heart (irregular heartbeat)
• Hair loss
• Vision problem
• Stomach pain, vomiting of blood, blood in stools.
• Yellowing of the skin, eyes, and dark urine.
• High blood sugar levels.
• Sensitivity to light
How To Use
Take Knilonat 150mg capsule as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking Knilonat 150mg capsule unless your doctor advises you to stop.
Safety Advice
• Breast Feeding: Taking Knilonat 150mg capsule while breastfeeding may be unsafe because it may affect the child. Therefore, talk with your doctor to get more information.
• Alcohol: It is unknown whether consuming alcohol while taking a Knilonat 150mg capsule is safe. Please speak with your physician.
• Liver: Inform your physician if you have liver problems because Knilonat 150mg capsule should be used cautiously with this condition. Before starting treatment, your physician conduct the liver function test.
• Lungs: It is unknown if patients with lung conditions can consume Knilonat 150mg capsule. So, before beginning the treatment, consult your doctor if you have any lung conditions. Consult your doctor if you experience symptoms like difficulty in breathing, wheezing or any other lung related condition while taking Knilonat 150mg capsule.
• Driving: While taking Knilonat 150mg capsule, it is unsafe to drive or use machines because it may cause nausea, changes in vision, vomiting, etc. Talk to your doctor for more information.
• Pregnancy: Knilonat 150mg capsule is unsafe to use during pregnancy unless it is necessary. Report to your doctor if you are pregnant or think you may be pregnant, or planning for the pregnancy before starting the treatment; your doctor will tell you whether you can take this medicine during your pregnancy.
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