Symbulardi 250mg capsule, contains active components as Saccharomyces boulardii. It is a probiotic yeast that is sometimes used as a medication or dietary supplement to support gastrointestinal health. It is commonly used to prevent or alleviate diarrhea that can occur as a side effect of antibiotic treatment. Antibiotics can disrupt the balance of gut bacteria, and it may help restore this balance. Travellers sometimes take it as a preventive measure to reduce the risk of developing diarrhoea while travelling to regions with different food and water hygiene standards. Some individuals with IBS, particularly those with diarrhoea-predominant IBS (IBS-D), use it to help manage their symptoms, although the evidence for its effectiveness in IBS is mixed. It may be used as a complementary therapy for individuals with Crohn's disease or ulcerative colitis. It may help reduce the frequency and severity of symptoms. Individuals with known allergies or sensitivities to yeast should avoid the medicine, as it is a type of yeast. The use of the drug is contraindicated in immunocompromised Individuals.  In patients with central venous catheters, there have been reports of fungemia (yeast in the bloodstream) associated with its use. It is generally not recommended for individuals with central venous catheters. It should be used cautiously in high-risk populations, including those with a history of recurrent fungal infections, critically ill patients, and those with severe underlying medical conditions.  The safety of the drug in infants under six months of age is not well established. In some cases, individuals with severe gastrointestinal disorders, such as pancreatitis or intestinal perforation, may need to avoid it, as it may not be appropriate for these conditions. It is typically not recommended for very young infants without specific guidance from a pediatrician.