Holoxan with uromitexan 2gm injection is an anticancer and cytoprotective drug belonging to the category of alkylating agents and hemorrhagic cystitis inhibitors, containing the active ingredient Ifosfamide and Mesna. These drugs are indicated for the treatment of bladder inflammation and cancers in the soft tissues, germ cells, pancreas, and cervix. Mesna mainly protects against some of the harmful effects of certain chemotherapy medications. If you had an allergic reaction to this drug or any of its components, it should not be used. This medicine may cause severe bone marrow suppression which results in low white blood cell count or low platelet count due to chemotherapy or radiation therapy. You should wait for three months before starting the treatment with this drug if you have received a live virus vaccine such as measles, mumps, rubella, or chickenpox. It is advised to use this drug with caution in severe kidney or liver-diseased individuals. Talk to your doctor if you take any other medications or before using over-the-counter medicines or herbal products. Your doctor will evaluate the risk of interaction with this medication. Consult your doctor before using this medication if you are pregnant or plan to have a baby. Holoxan with uromitexan 2gm injection is unsafe to use during pregnancy as it causes harm to an unborn fetus. Your healthcare practitioner will conduct a pregnancy test before you start treatment with this drug. Discuss with your doctor effective birth control methods and utilize them for at least two weeks following the last dose. Breastfeeding should be avoided during the treatment with this drug as it may pass into breast milk in small amounts.