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Desferal 500mg Injection
Manufacturer/Marketed By : NOVARTIS INDIA LTD
$3.22 $3.22
Desferal 500mg Injection contains an active component as deferoxamine. This medication is used to treat iron overload in the body. It belongs to a class of drugs called iron-chelating agents....
DEFEROXAMINE
Active Pharmaceutical Ingredient
Desferal 500mg Injection
$3.22
Desferal 500mg Injection contains an active component as deferoxamine. This medication is used to treat iron overload in the body. It belongs to a class of drugs called iron-chelating agents. Iron overload diseases are thalassemia, hemochromatosis, sickle cell disease, myelodysplastic syndromes, chronic transfusions and iron poisoning. Thalassemia is an inherited blood disorder causing abnormal hemoglobin production and anemia. Hemochromatosis is a hereditary condition with excessive iron absorption, leading to iron overload in organs. Sickle cell disease is a genetic disorder affecting red blood cell shape, causing pain and organ damage. Myelodysplastic syndromes are blood disorders affecting the bone marrow, leading to abnormal blood cell production. Chronic transfusions are required for severe anemia or blood disorders, leading to iron overload. Iron poisoning occurs when toxic amounts of iron are ingested and treated with Desferal 500mg Injection to eliminate excess iron from the body. Iron overload can occur in conditions such as thalassemia, hemochromatosis, or chronic transfusions, where excessive iron accumulates in organs and tissues, potentially causing damage. By managing iron overload, Desferal 500mg Injection can improve the quality of life for individuals with conditions that cause iron accumulation. It may help reduce symptoms like fatigue, joint pain, and other complications associated with iron overload. Properly managing iron overload with this medication can help prolong the life expectancy of individuals with iron-related disorders by preventing severe organ damage and complications. Iron overload can lead to serious complications like liver disease, heart problems, and endocrine disorders. By reducing excess iron levels, it helps lower the risk of such complications. Individuals with a known allergy to Desferal 500mg Injection or any of its components should not use this medication. Allergic reactions can range from mild skin rashes to severe anaphylactic reactions, which can be life-threatening. This is primarily excreted by the kidneys. Patients with significant kidney impairment may not be suitable candidates for Desferal 500mg Injection therapy or may require dosage adjustments and close monitoring. This medication has been associated with potential hearing and vision disturbances in some patients. Individuals with pre-existing hearing or vision problems should be cautious and may require more frequent monitoring. It is not suitable for treating iron deficiency anemia. It can exacerbate iron deficiency, so it should not be used in individuals with low iron levels. While this medication can be used in pediatric patients, careful monitoring and appropriate dosage adjustments based on weight and individual needs are essential.
Active Pharmaceutical Ingredient
Uses
• Thalassemia
• Hemochromatosis
• Sickle cell disease
• Myelodysplastic syndromes
• Chronic transfusions
• Iron poisoning
Benefits
The mechanism of action of Desferal 500mg Injection involves chelation, a process by which the drug binds to excess iron in the body. It forms stable complexes with free iron ions, particularly the trivalent iron, creating water-soluble compounds. These iron-deferoxamine complexes are then excreted primarily through the urine, effectively removing the excess iron from the bloodstream and tissues. By reducing iron levels, this medication helps to prevent iron-related oxidative damage to organs and tissues, mitigating the risk of organ dysfunction and other complications associated with iron overload conditions such as thalassemia, hemochromatosis, and chronic transfusions.
Side Effects
Desferal 500mg Injection causes some side effects like all medications, although not everyone will experience them.
Most Common Side Effects
• Pain, swelling, redness, and itching at the injection site
• Headache
• Reddish-brown color of urine
• Nausea
• Fever, feeling sick
• Slow growth in children under age three
Common Side Effects
• Tightness of chest with wheezing or coughing and difficulty in breathing
• Allergic reactions (facial and throat swelling, feeling faint, rash)
• Decreased urine output
• Seizures
• Infections (fever accompanied by stomach pain and shortness of breath)
How To Use
Healthcare professionals typically administer Desferal 500mg Injection in a hospital or clinical setting. The injection may be given as an injection, depending on the treatment condition and the healthcare provider's instructions. Before administration, the healthcare professional will assess the patient's patient's medical history, current health status, and any known allergies or sensitivities.
Safety Advice
• Breast Feeding: The safety of Desferal 500mg Injection in breastfeeding has not been established, and there is a concern about the potential adverse effects it may have on the nursing baby.
• Alcohol: Both Desferal 500mg Injection and alcohol can potentially affect the liver. Combining the two may increase the risk of liver damage or worsen pre-existing liver conditions.
• Liver: Desferal 500mg Injection is generally considered safe to use in individuals with normal liver function. However, caution should be exercised in patients with pre-existing liver conditions or liver impairment.
• Lungs: Desferal 500mg Injection is generally safe to use in individuals with normal lung function. However, caution should be exercised in patients with pre-existing lung conditions or compromised respiratory function.
• Driving: Common side effects of Desferal 500mg Injection may include dizziness, headache, and visual disturbances. If a person experiences any of these side effects while taking, it is essential to avoid driving or operating heavy machinery until they feel fully alert and able to concentrate.
• Pregnancy: Desferal 500mg Injection use during pregnancy with caution and only used after consulting a healthcare provider.
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