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Biotrexate 500mg Injection
Manufacturer/Marketed By : ZYDUS CADILA
$12.04 $4.81
Biotrexate 500mg Injection contains the active substance Methotrexate. It is an anti-metabolite and immunosuppressant drug. It treats certain types of cancer, such as acute lymphocytic leukemia (ALL), meningeal leukemia, non-hodgkin’s...
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METHOTREXATE
Active Pharmaceutical Ingredient
Biotrexate 500mg Injection
$12.04
$4.81
Biotrexate 500mg Injection contains the active substance Methotrexate. It is an anti-metabolite and immunosuppressant drug. It treats certain types of cancer, such as acute lymphocytic leukemia (ALL), meningeal leukemia, non-hodgkin’s lymphoma, osteosarcoma, cutaneous T-cell lymphoma, breast cancer, and head and neck cancer in adults. It is also used to treat severe psoriasis in adults (a skin disease in which red, scaly patches form on some body areas). It is also indicated to treat rheumatoid arthritis in adults. Do not use Biotrexate 500mg Injection if you are allergic to methotrexate or any of the other ingredients of this medicine. Do not take this medicine if you have kidney or liver problems, blood disorders, weakened immune system, pregnant, or breastfeeding. Inform your physician immediately if you experience any symptoms of spitting and coughing up blood, general muscle weakness, vision disturbance, changes in thinking, memory, and orientation problems. This medicine may impair fertility. Avoid getting pregnant during the treatment and for six months after the last dose. Tell your doctor if you have a stomach ulcer, active infection, or mild kidney problems and about any recent vaccinations before starting the treatment. Biotrexate 500mg Injection can cause serious side effects even with low doses; hence, regular follow-ups and routine laboratory tests will be necessary as a precaution. Do not use this medicine if you are pregnant, breastfeeding, or planning to get pregnant.
Active Pharmaceutical Ingredient
Uses
• To treat certain types of cancers
• To treat severe psoriasis
• To treat rheumatoid arthritis
Benefits
Biotrexate 500mg Injection inhibits dihydrofolic acid reductase. Therefore, this medicine interferes with DNA synthesis, repair, and cellular replication. Actively proliferating tissues such as malignant cells, bone marrow, fetal cells, buccal and intestinal mucosa, and urinary bladder cells are, in general, more sensitive to this medicine. Blocking these slows down how fast cancer cells grow, spread, and suppress the immune system in autoimmune diseases.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Most Common Side Effects
• Severe allergic reactions
• Spitting or coughing blood
• Chest pain
• Weakness on one side of the body
• Muscle weakness
Common Side Effects
• Hairloss
• Photosensitivity
• Rash
• Diarrhea, Nausea and Vomiting
• Decreased WBC and platelet count
• Dizziness
• Tiredness, fever, and shivering
• Blurred vision
How To Use
Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, your physician decides the dose, dosage, and frequency of this injection. Biotrexate 500mg Injection is injected into a vein (intravenously) or into muscle (intramuscularly). Do not self-administer this medicine.
Safety Advice
• Breast Feeding: Breastfeeding is not recommended in patients taking Biotrexate 500mg Injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
• Alcohol: It is unsafe to drink alcohol while you take Biotrexate 500mg Injection because it may cause damage to your liver.
• Liver: Biotrexate 500mg Injection is contraindicated in patients with acute liver failure. Dose adjustments are necessary if you have liver problems. Inform your physician if you have any liver disease before initiating the therapy.
• Lungs: Biotrexate 500mg Injection should be cautiously used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
• Driving: Do not drive or operate heavy machinery if you experience any side effects such as dizziness, drowsiness, or blurred vision.
• Pregnancy: Do not use Biotrexate 500mg Injection during pregnancy because it can cause birth defects. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for six months after the last dose.
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