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Azadine O 200mg Tablet
Manufacturer/Marketed By : INTAS PHARMACEUTICALS LTD
$159.73 $132.58
Azadine O 200mg Tablet is used for treating adults with Myelodysplastic syndrome (MDS) and Acute myeloid leukemia (AML) if they are considered ineligible for stem cell transplant. In Myelodysplastic Syndrome,...
AZACITIDINE
Active Pharmaceutical Ingredient
Azadine O 200mg Tablet
$159.73
$132.58
Azadine O 200mg Tablet is used for treating adults with Myelodysplastic syndrome (MDS) and Acute myeloid leukemia (AML) if they are considered ineligible for stem cell transplant. In Myelodysplastic Syndrome, the bone marrow does not produce healthy blood cells due to its lack of function. Acute Myeloid Leukemia is a type of bone marrow cancer caused by the release of incompletely formed blood cells into the bloodstream.
Active Pharmaceutical Ingredient
Uses
• Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant
• Intermediate-2 and High-risk Myelodysplastic syndrome (MDS)
Benefits
In MDS and AML, the development of tumor cells is caused by the process of transcriptional repression of various genes, which is due to the hypermethylation of DNA. Transcriptional repression is a process where proteins bind directly or indirectly to DNA and control the activity of copying a specific gene or a set of genes. The active form of Azadine O 200mg Tablet binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Most Common Side Effects
• Disturbances in the blood count (RBC, WBC, Platelets)
• Nausea, vomiting, diarrhea
• Constipation
• Tiredness
• Skin reactions like redness and pain at the site of injection
• Decreased appetite
• Dizziness
• Pain in extremities
• Joint pain
• Stomach pain
• Headache
• Sore nose and throat
• Rashes and bruising
Common Side Effects
• Unexpected bleeding, with blood in stool and urine
• Fever
• Pneumonia is characterised by chest pain or breathlessness.
• Allergic reaction with symptoms of swelling of lips, itching, or rashes.
• Seizures, loss of consciousness, severe headache, or bleeding in the brain
• Frequent urination with pain or burning sensation
How To Use
Take Azadine O 200mg Tablet only under the supervision of your physician. Your physician will decide the dose based on your height, weight, and general condition. It shall be given under the skin of your thigh, stomach, or upper arm.
Safety Advice
• Breast Feeding: Breastfeeding is not intended for patients on Azadine O 200mg Tablet therapy. Consult your physician for advice.
• Alcohol: It is not known whether it is safe to consume alcohol with Azadine O 200mg Tablet. Please consult your doctor.
• Liver: Inform your physician if you have been told that you have a tumor in the liver cells.
• Lungs: It is not known whether it is safe to administer Azadine O 200mg Tablet in lung failure patients. Please consult your doctor.
• Driving: It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking Azadine O 200mg Table.
• Pregnancy: Azadine O 200mg Tablet could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.
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