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Kryxana 200mg Tablet
Manufacturer/Marketed By : NOVARTIS INDIA LTD
$259.35 $222.55
Kryxana 200mg Tablet is an oral small-molecule inhibitor classified under cyclin-dependent kinase (CDK) 4/6 inhibitors. It contains the active ingredient ribociclib succinate, equivalent to 200 mg of ribociclib per tablet....
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RIBOCICLIB
Active Pharmaceutical Ingredient
Kryxana 200mg Tablet
259,35$
222,55$
Kryxana 200mg Tablet is an oral small-molecule inhibitor classified under cyclin-dependent kinase (CDK) 4/6 inhibitors. It contains the active ingredient ribociclib succinate, equivalent to 200 mg of ribociclib per tablet. This medication is prescribed primarily for adults with hormone receptor (HR)-positive, HER2-negative breast cancer, both in advanced/metastatic and early-stage high-risk settings. It works by halting cancer cell division, helping delay progression or recurrence. Before starting, consult a physician experienced in oncology. Do not use if you have known allergies to ribociclib, peanuts, soya, or any excipients. Inform your doctor if you have liver, kidney, or heart issues, especially conditions affecting the QT interval. Regular monitoring of blood counts, liver function, and ECG is essential. Pregnancy and breastfeeding are contraindications; effective contraception is required during treatment and for at least 3 weeks after the last dose.
Active Pharmaceutical Ingredient
Uses
• Advanced or metastatic breast cancer
• Advanced or metastatic endometrial cancer
Benefits
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Side Effects
Side Effects:
Most Common Side Effects
• Neutropenia
• Nausea, diarrhea, constipation
• Vomiting
• Fatigue, headache
• Hair thinning or loss
• Rash, cough
Common Side Effects
• QT interval prolongation
• Hepatobiliary toxicity (liver enzyme elevations)
• Pneumonitis/interstitial lung disease
• Severe neutropenia (low white blood cell counts)
How To Use
The recommended dose is 600 mg daily, which equates to three 200 mg film-coated tablets, taken orally once a day for 21 consecutive days followed by a 7-day break, completing a 28-day cycle. Tablets should be swallowed whole with or without food, preferably at the same time each morning to maintain consistent levels. Dose may be reduced to 400 mg or 200 mg in case of intolerance or drug interactions.
Safety Advice
• Breast Feeding: Kryxana 200 mg Tablet is unsafe for use during breastfeeding. Because of the potential risk to the infant, breastfeeding is not recommended during treatment.
• Alcohol: It is generally recommended that patients taking Kryxana 200mg Tablet avoid or limit their alcohol intake, as alcohol can increase the risk of liver damage and exacerbate any liver-related side effect.
• Liver: Regular monitoring of liver function tests is recommended because it has been associated with liver injury in some patients. It is important to monitor liver function regularly in patients taking Kryxana 200mg Tablet, particularly in those with pre-existing liver disease or a history of liver problems. It is unsafe for the patients having liver failure.
• Lungs: Kryxana 200mg Tablet has been associated with some lung-related side effects, although these are relatively uncommon. Consult your doctor if you have any lung diseases before starting the treatment.
• Driving: Kryxana 200mg Tablet may cause side effects such as fatigue, dizziness, or blurred vision that can impair a patient's ability to drive or operate machinery safely. So it is not recommended to drive or operate machinery safely while treatment.
• Pregnancy: Kryxana 200mg Tablet is unsafe for pregnant women as it may cause foetal harm if taken during pregnancy. So it is recommended to avoid it during pregnancy.
Disclaimer
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