Besponsa 1 mg Injection
3.739,80$
2.917,04$
Besponsa 1 mg injection is a specialized treatment designed for adults battling relapsed or refractory CD22-positive B cell precursor acute lymphoblastic leukemia (ALL), a severe form of blood cancer. This medication is particularly indicated for those who have Philadelphia chromosome positive (Ph+) ALL and have previously been treated with at least one tyrosine kinase inhibitor (TKI), making it a vital option for patients who have exhausted other therapies. By targeting the CD22 antigen on the surface of B cell leukemia cells, Besponsa works to inhibit their growth and proliferation, offering hope for better outcomes in challenging cases. It’s important to note that Besponsa is not recommended for children, as its safety and effectiveness in pediatric populations have yet to be established. Patients should consult with their healthcare provider to discuss potential side effects and contraindications before starting treatment. As a potent therapeutic option, Besponsa represents a significant advancement in the management of this aggressive leukemia type. With ongoing research and clinical evaluation, it continues to play a crucial role in improving the prognosis for adult patients facing relapsed or refractory ALL.
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Active Pharmaceutical Ingredient
Uses
• Besponsa 1 mg injection is primarily used in the treatment of acute lymphoblastic leukemia (ALL), a type of blood cancer that affects the white blood cells. This medication targets and helps eliminate cancerous cells in the body. By doing so, it contributes to the overall management of the disease, potentially improving patient outcomes. Healthcare providers often consider this treatment option for patients who have specific genetic markers associated with ALL.
• In cases where patients have relapsed or refractory acute lymphoblastic leukemia, Besponsa 1 mg injection can play a crucial role in their treatment plan. It is designed to target leukemia cells more effectively, thereby enhancing the chances of remission. This makes it a vital option for those who have not responded to previous therapies. Oncologists may recommend Besponsa to help patients regain control over their health.
• Besponsa 1 mg injection is also utilized in conjunction with other therapies to optimize treatment effectiveness. By integrating this medication into a comprehensive care strategy, healthcare providers can tailor treatment to the individual needs of patients. This combination approach can lead to improved management of acute lymphoblastic leukemia. It exemplifies the ongoing advancements in cancer treatment options available today.
• For certain patient populations with acute lymphoblastic leukemia, Besponsa 1 mg injection offers a targeted mechanism of action that can reduce the burden of the disease. It is particularly beneficial for those with specific genetic abnormalities that drive their leukemia. The precise targeting of cancer cells helps to minimize damage to healthy cells, which is an important consideration in cancer therapy. As such, Besponsa is a valuable tool in the fight against this aggressive form of leukemia.
Benefits
Acute lymphoblastic leukemia (Blood cancer): Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. Besponsa 1 mg Injection kills or stops the growth of cancer cells and prevents the multiplication of cancer cells. It is a potent and very toxic medicine, and you should discuss its risks and benefits with your doctor. Avoid drinking alcohol during the treatment with this drug and drink plenty of water to stay hydrated.
Side Effects
Like all medications, Besponsa 1 mg Injection can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.
Most Common Side Effects
• Low blood count
• Fatigue
• Nausea
• Rise in Liver enzymes
• Wheezing
• Headache
• Chills
• Nosebleed
• Vomiting
• Anorexia
• Constipation
• Yellow skin
• Tiredness
• Dark Urine
Common Side Effects
• occlusive Disease
• Bleeding
• High Fever
• Shortness of Breath
• Closing of Throat
• Difficult Breathing
• Frequent Diarrhea
• Hematuria
• Painful and Swollen Mouth ulcers
• Painful and burning urination
How To Use
Besponsa 1 mg Injection is given by a trained doctor or nurse at a hospital or clinical setting. Do not self-administer the Besponsa 1 mg Injection. Your doctor will decide the dose and duration of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion, and you will be monitored carefully for unwanted side effects.
Safety Advice
• Alcohol: It is generally not recommended to drink alcohol while taking Besponsa 1 mg Injection. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.
• Kidney: Besponsa 1 mg Injection is safe for use in mild, moderate or severe kidney disease patients. No adjustment to the starting dose is required in patients with mild, moderate, or severe renal impairment (creatinine clearance [CLcr] 60-89 mL/min, 30-59 mL/min, or 15-29 mL/min. The safety and efficacy of Besponsa 1 mg have not been studied in patients with end-stage renal disease.
• Breastfeeding: It is not recommended to breastfeed while taking Besponsa 1 mg. Besponsa 1 mg Injection may pass into breast milk and harm the infant. If you are breastfeeding and taking Besponsa 1 mg Injection, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.
• Liver: Besponsa 1 mg Injection is safe to use in patients with liver disease. No dose adjustment of Besponsa 1 mg is recommended.
• Pregnancy: Use of Besponsa 1 mg Injection may be unsafe during pregnancy as animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Besponsa 1 mg during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.
• Driving: Besponsa 1 mg Injection has moderate influence on the ability to drive and use machines. Patients may experience fatigue during treatment with Besponsa 1 mg. Therefore, caution is recommended when driving or operating machines.