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Venclexta 100mg Tablet
Manufacturer/Marketed By : ABBVIE THERAPEUTICS INDIA PVT LTD
$136.71 $120.33
Venclexta 100mg Tablet contains the active ingredient Venetoclax. Venclexta 100mg Tablet is an antineoplastic drug that belongs to the class of BCL-2 inhibitors. It is used to treat adults with...
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VENETOCLAX
Active Pharmaceutical Ingredient
Venclexta 100mg Tablet
$136.71
$120.33
Venclexta 100mg Tablet contains the active ingredient Venetoclax. Venclexta 100mg Tablet is an antineoplastic drug that belongs to the class of BCL-2 inhibitors. It is used to treat adults with certain types of blood cancers, including chronic lymphocytic leukaemia (CLL) and acute myeloid leukaemia (AML). Specifically, it is used in CLL with a 17p deletion and in AML in patients who cannot undergo intensive chemotherapy. Additionally, it can be used in combination with other medications to treat certain types of non-Hodgkin lymphoma. Venclexta 100mg Tablet works by inhibiting the BCL-2 protein, which helps promote cancer cell death. This action restores the process of apoptosis (programmed cell death) by binding to BCL-2, displacing pro-apoptotic proteins, and initiating mitochondrial outer membrane permeabilisation, which triggers cell death. Do not take Venclexta 100mg Tablet if you are allergic to Venetoclax or any of the other ingredients in the medication. Before starting treatment, inform your doctor if you have kidney problems, a history of infections, or any blood-related disorders like low white blood cell count or low platelet count. Ensure that your physician is aware of any past history of Tumor Lysis Syndrome (TLS) or if you are pregnant or planning to become pregnant, as Venclexta may harm the fetus. Venclexta 100mg Tablet should not be used in children or adolescents under the age of 18.
Active Pharmaceutical Ingredient
Uses
• Chronic lymphocytic leukaemia (CLL), including CLL with 17p deletion
• Acute myeloid leukaemia (AML) in adults who cannot undergo intensive chemotherapy
• Certain types of non-Hodgkin lymphoma, when combined with other medications
Benefits
Venclexta 100mg Tablet works as a selective, orally bioavailable small-molecule inhibitor of BCL-2, an antiapoptotic protein. In CLL and AML cells, BCL-2 overexpression supports tumour cell survival and chemotherapy resistance by binding directly to BCL-2, Venclexta 100mg Tablet displaces pro-apoptotic proteins like BIM, triggering mitochondrial outer membrane permeabilisation and activating caspases. Nonclinical studies demonstrate venetoclax’s cytotoxic effect on tumor cells overexpressing BCL-2.
Side Effects
Side effects are unwanted symptoms caused by medicines. Although all drugs can cause side effects, not everyone experiences them.
Most Common Side Effects
• Risk of death
• Tumor lysis syndrome (TLS)
• Kidney failure
• Need for dialysis treatment
Common Side Effects
• Fatigue
• Anemia
• Nausea
• Diarrhea
• Low platelet count (thrombocytopenia)
• Low white blood cell count (neutropenia)
How To Use
Venclexta 100mg Tablet is administered orally. Do not break, chew, or crush the tablets. Follow the prescribed dosing schedule and consult your healthcare provider to determine the correct dosage. If you miss a dose, do not double the dose. Contact your healthcare provider for guidance.
Safety Advice
• Breast Feeding: It is unknown if Venclexta 100mg Tablet are safe to take during breastfeeding. Please consult your healthcare provider if you have any concerns.
• Alcohol: It is unknown whether alcohol consumption is safe while you are undergoing a Venclexta 100mg Tablet course. It is recommended to consult your doctor for better guidance.
• Liver: If you have any pre-existing lung conditions, discuss them with your doctor before starting treatment with Venclexta 100mg Tablet.
• Lungs: If you have any pre-existing lung conditions, discuss them with your doctor before starting treatment with Venclexta 100mg Tablet.
• Driving: Venclexta 100mg Tablet has no or negligible influence on the ability to drive and use machines, so it is generally safe to use.
• Pregnancy: It is unsafe to consume Venclexta 100mg Tablet during pregnancy as it may cause harm to the fetus when administered to pregnant women.
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