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Veltiro 500mg Injection
Manufacturer/Marketed By : ZYDUS CADILA
$425.86 $109.07
Veltiro 500mg injection contains the active constituent rituximab. It is used for several different disease conditions in adults. It is used alone or with other medications to treat non-hodgkin’s lymphoma...
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RITUXIMAB
Active Pharmaceutical Ingredient
Veltiro 500mg Injection
$425.86
$109.07
Veltiro 500mg injection contains the active constituent rituximab. It is used for several different disease conditions in adults. It is used alone or with other medications to treat non-hodgkin’s lymphoma (cancer affecting white blood cells called B-lymphocytes) and chronic lymphocytic leukemia (a most common form of cancer that affects B-cells). It is also indicated to treat moderate-to-severe rheumatoid arthritis (a type of disease where the immune system attacks the body cells of its own joints) in combination with methotrexate in adults. Other uses include granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels that mainly affects the lungs and kidneys) in adults and children 2 years of age and older. It is also used to treat moderate to severe pemphigus vulgaris (an autoimmune condition that causes painful blisters on the skin and lining of the mouth, throat, nose, and genitals. Veltiro 500mg injection belongs to the class of medications called anti-CD20 monoclonal antibodies. Do not take this injection if you are allergic to rituximab or any other ingredients of this medicine, have a weak immune system, or have any severe active infection. Inform your physician if you have heart disease, heart failure, or breathing problems before initiating the treatment. Talk with your doctor if you have ever had a hepatitis B infection because the infection may reactivate again in a few cases and can be severe sometimes. Pregnancy and breastfeeding are not recommended when you are taking this injection. Common side effects of Veltiro 500mg injection include infection of the blood, reduced red blood cells, dizziness, swelling in the face and body, itchy skin, diarrhea, increased sweating, and low or high blood pressure. Use effective contraceptives during the treatment and 12 months after the last dose if you can get pregnant. This medicine may cause severe infusion reactions during or within 24 hours after administration. Inform your physician or healthcare professional if you face any infusion reactions, such as increased blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rashes, or throat swelling.
Active Pharmaceutical Ingredient
Uses
• Non-hodgkin’s lymphoma (NHL)
• Chronic lymphocytic leukemia (CLL)
• Rheumatoid Arthritis
• Granulomatosis with polyangiitis or microscopic polyangiitis
• Pemphigus vulgaris
Benefits
Veltiro 500mg injection is a monoclonal antibody that targets the antigen CD20 expressed on the cell surface of B-lymphocytes (a type of white blood cells). When this medicine binds to the B-cell, it induces cell death in NHL and CLL. The binding action blocks cell activation and growth and cause anticancer effects. It inhibits rheumatoid factor production, antigen presentation, T-cell activation, and proinflammatory cytokine production in rheumatoid arthritis.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Most Common Side Effects
• Increased or decreased blood pressure
• Chest pain
• Hypersensitivity reactions
• Hepatitis B viral infection
• Memory loss, trouble thinking, difficulty in walking
Common Side Effects
• Swelling in the face and body
• Diarrhea and nausea
• Itchy skin
• Anemia
• Muscle spasm
• Headache
• Urinary tract infection
• Fever, chills, and shivering
• Inflammation of nasal cavities
• Cough, sore throat
• Loss of hair
How To Use
It should only be administered by a trained doctor or nurse. Do not self-administer the injection. Before giving Veltiro 500mg injection, you will be given other medications (pre-medication) to reduce the possible side effects. Your doctor will decide the dose and duration of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion, and you will be monitored carefully for any unwanted side effects.
Safety Advice
• Breast Feeding: Breastfeeding is not recommended in patients taking Veltiro 500mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.
• Alcohol: Consuming alcohol may affect the effectiveness of Veltiro 500mg injection. Stop consuming alcohol if you are taking this medicine.
• Liver: Whether Veltiro 500mg injection can be used in patients with liver impairment is unknown. Consult your doctor if you have or ever had liver disease or hepatitis B infection before starting the treatment. The reactivation of hepatitis viral infection can cause severe liver problems.
• Lungs: It is unknown whether Veltiro 500mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
• Driving: Caution is required while driving and operating machinery when you take Veltiro 500mg injection because it may cause dizziness, sleepiness, tiredness, and risk of falling.
• Pregnancy: Veltiro 500mg injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.
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