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Koselugo 25mg Capsule
Manufacturer/Marketed By : ASTRAZENECA PHARMA INDIA LTD
$10882.68 $8923.81
Koselugo 25mg Capsule contains an active component called Selumetinib. It is a medication used in the treatment of certain types of cancers, particularly melanoma (a type of skin cancer) and...
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SELUMETINIB
Active Pharmaceutical Ingredient
Koselugo 25mg Capsule
$10,882.68
$8,923.81
Koselugo 25mg Capsule contains an active component called Selumetinib. It is a medication used in the treatment of certain types of cancers, particularly melanoma (a type of skin cancer) and other solid tumors, including non-small cell lung cancer and ovarian cancer, especially in cases where there's a specific genetic mutation that makes the cancer cells sensitive to MEK inhibitors. It may be prescribed for patients with advanced melanoma that has a specific genetic mutation, often BRAF-mutant melanoma. It has shown promise in treating plexiform neurofibromas, tumors associated with NF1, a genetic disorder that causes tumors to grow on nerves. Individuals who have had a severe allergic reaction to Koselugo 25mg Capsule or any of its components should not take this medication. It may cause harm to an unborn baby, so it is not recommended for use during pregnancy. Patients with pre-existing heart conditions or a history of heart problems may need close monitoring or might not be suitable candidates for this medication. Older individuals, especially those over 65, may have an increased risk of certain side effects. Close monitoring for adverse reactions is typically recommended after taking this medication. The safety and efficacy of Koselugo 25mg Capsule in children under specific ages may not be well-established.
Active Pharmaceutical Ingredient
Uses
• Melanoma treatment
• Neurofibromatosis type 1 (NF1)
• Solid tumor treatment
Benefits
Koselugo 25mg Capsule is a medication that targets a specific cellular pathway called the MEK pathway, which is crucial for regulating cell growth. In cancers like melanoma and certain tumors, it blocks this pathway, disrupting signals that promote uncontrolled cell growth. By inhibiting this pathway, it slows down or halts the progression of cancer cells, reducing tumor growth and spread.
Side Effects
Koselugo 25mg Capsule causes some side effects like all medications, although not everyone will experience them.
Most Common Side Effects
• Nausea and vomiting
• Diarrhea
• Fatigue
• Skin rash
• Swelling or fluid retention
Common Side Effects
• Heart problems
• Eye problems
• Interstitial lung disease (ILD)
• Liver problems
• Skin toxicities
How To Use
Koselugo 25mg Capsule is primarily administered orally, typically as capsules. The healthcare provider will determine the dosage and duration of treatment based on the specific infection and individual factors.
Safety Advice
• Breast Feeding: It is not safe to breastfeed while taking Koselugo 25mg Capsule, as it may pass into breast milk and harm the infant.
• Alcohol: There are no specific interactions between alcohol and Koselugo 25mg Capsule, but alcohol consumption might exacerbate certain side effects, such as dizziness or liver-related problems. It is advisable to consult a healthcare professional regarding alcohol consumption while on this medication.
• Liver: If you have a liver condition or are concerned about the safety of Koselugo 25mg Capsule, it is recommended to consult your healthcare provider for personalized advice.
• Lungs: Consult your health care provider before taking Koselugo 25mg Capsule if you have lung disease.
• Driving: Taking Koselugo 25mg Capsule while driving is unsafe as it might cause dizziness or visual disturbances as side effects, which could affect the ability to drive or operate machinery.
• Pregnancy: It is not safe to take Koselugo 25mg Capsule during pregnancy as it may cause harm to the unborn baby.
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