Actemra 400 mg Injection
$547.00
$373.81
Actemra 400 mg injection is an effective treatment option designed to manage various inflammatory conditions such as rheumatoid arthritis, ankylosing spondylitis, psoriasis, ulcerative colitis, and Crohn's disease. As a disease-modifying anti-rheumatic drug (DMARD), this monoclonal antibody functions by targeting and inhibiting the activity of tumor necrosis factor-alpha (TNFα), a key player in inflammation. By doing so, Actemra significantly alleviates symptoms like swelling, pain, and redness, while enhancing overall physical function and quality of life for patients. It's essential to note that Actemra may not be suitable for everyone; patients should discuss their medical history with healthcare providers to understand potential risks and side effects, including serious infections. Regular monitoring is advised during treatment to ensure safety and efficacy. With its targeted approach to immune modulation, Actemra offers hope for those seeking relief from debilitating autoimmune conditions. Always consult with a healthcare professional before starting or adjusting any medication regimen to ensure the best outcomes for your health.
मात्रा
Active Pharmaceutical Ingredient
Uses
• Actemra 400 mg injection is commonly used to treat moderate to severe rheumatoid arthritis in adults. This medication helps to reduce inflammation and improve physical function by targeting specific pathways in the immune system. Patients often experience a decrease in joint pain and swelling, allowing for better mobility and quality of life. It is typically prescribed when other therapies have not been effective.
• In the case of juvenile idiopathic arthritis, Actemra 400 mg injection serves as an effective treatment option for children aged two years and older. This medication helps to alleviate symptoms such as joint stiffness and swelling. By modulating the immune response, Actemra promotes improved physical function and well-being in young patients. It is an important part of a comprehensive treatment plan for managing this condition.
• Actemra 400 mg injection is also indicated for the treatment of giant cell arteritis, a condition characterized by inflammation of the blood vessels. This medication helps to reduce the inflammatory response, thereby preventing complications related to the disease. Patients often notice a significant improvement in symptoms, including headaches and vision problems. Actemra is typically used when other treatments are insufficient to control the disease.
• Another condition treated with Actemra 400 mg injection is polyarticular juvenile idiopathic arthritis. This formulation aids in managing the symptoms associated with this chronic condition in younger patients. By targeting specific inflammatory processes, Actemra helps to decrease joint inflammation and improve overall function. It plays a crucial role in helping children lead more active and fulfilling lives despite their diagnosis.
Benefits
Rheumatoid arthritis: Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects the joints. It causes inflammation, pain, stiffness, and swelling in the joints, and can also affect other parts of the body, such as the skin, eyes, lungs, heart, and blood vessels. Actemra 400 mg helps reduce inflammation and manage the symptoms of Rheumatoid arthritis.
Ankylosing spondylitis: Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the spine, causing pain, stiffness, and reduced mobility. It is a form of arthritis that mainly affects the joints between the vertebrae in the spine and the sacroiliac joints where the spine connects to the pelvis. Actemra Injection works by targeting and inhibiting tumour necrosis factor (TNF), a protein involved in inflammation. By reducing the inflammation associated with ankylosing spondylitis, Actemra 400 mg Injection can help relieve pain, stiffness, and other symptoms of the condition.
Crohn's disease: Crohn's disease is a chronic inflammatory bowel disease (IBD) that primarily affects the gastrointestinal tract. It can cause inflammation and damage to any part of the digestive system, from the mouth to the anus. Symptoms of Crohn's disease can vary but commonly include abdominal pain, diarrhoea, weight loss, fatigue, and loss of appetite. Actemra 400 mg works by targeting and inhibiting tumour necrosis factor (TNF), a protein involved in inflammation. By reducing inflammation in the gastrointestinal tract, Actemra 400 mg Injection can help manage the symptoms of Crohn's disease, including abdominal pain, diarrhoea, and inflammation.
Ulcerative colitis: Ulcerative colitis is a chronic inflammatory bowel disease that primarily affects the colon and rectum. Actemra Injection can help reduce inflammation in the gastrointestinal tract and manage the symptoms of ulcerative colitis.
Hidradenitis suppurativa: Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that affects the hair follicles in areas of the body with a high concentration of sweat glands, such as the armpits, groin, and buttocks. Actemra 400 mg works by targeting and inhibiting tumour necrosis factor (TNF), a protein involved in inflammation. By reducing inflammation, Actemra 400 mg Injection can help alleviate symptoms and prevent the progression of hidradenitis suppurativa.
Juvenile idiopathic arthritis: Juvenile idiopathic arthritis (JIA) is a type of arthritis that occurs in children under the age of 16 and persists for at least six weeks. It is characterized by joint inflammation, pain, stiffness, and swelling. Actemra 400 mg Injection works by inhibiting tumour necrosis factor (TNF), a protein involved in inflammation. By reducing inflammation in the joints, adalimumab helps manage the symptoms of Juvenile idiopathic arthritis, including pain, stiffness, and swelling. Plaque psoriasis: Psoriasis is a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Actemra Injection reduces the scaly, itchy patches which may develop on the different parts of the body. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Psoriatic arthritis: Psoriatic arthritis is a type of inflammatory arthritis that occurs in some individuals with psoriasis, a chronic skin condition. It causes joint pain, swelling, and stiffness, and can affect any joint in the body. Actemra 400 mg Injection works by inhibiting tumour necrosis factor (TNF), a protein involved in inflammation. By reducing inflammation in the joints, adalimumab can help manage the symptoms of psoriatic arthritis, including joint pain, stiffness, and swelling.
Uveitis: Uveitis refers to the inflammation of the uvea, which is the middle layer of the eye. It can affect various parts of the uvea, including the iris, ciliary body, and choroid. Actemra 400 mg is a tumour necrosis factor (TNF) inhibitor that helps reduce inflammation by targeting TNF, a protein involved in the immune response.
Side Effects
As with all medicines, Actemra 400 mg Injection may cause side effects which do not require medical attention and which will disappear as your body adjusts to the medicine. If they persist or you're concerned about them, tell your doctor.
Most Common Side Effects
• Diarrhoea
• Headache
• Throat, Nasal and Chest infections
• Skin infections
• Tiredness
• Yellow Eyes and Skin.
• Appetite loss
• Vomiting
• Darker Urine and Tarry stool
• skin rashes
• Short breathing
• Chest pain
• Coughing and Sneezing with blood and Mucus
• redness and Swelling of Skin
• painful Urination
• Weigh loss
• Changes in Frequency and Consistency of passing stool.
Common Side Effects
• Blood Clots
• sudden shortness of Breath
• Painful Breathing
• Chest Pain
• Heavy Sweating
• Redness, Painful and Swollen limbs.
How To Use
Actemra 400 mg Injection is given subcutaneously (under the skin) from any health care professional. Dosage and frequency will be decided by your doctor as per your disease condition and several other factors.
Safety Advice
• Alcohol: It is generally not recommended to drink alcohol while taking Actemra 400 Injection. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.
• Kidney: patients with kidney disease should closely monitor kidney function while taking Actemra 400 mg Injection and report any unusual symptoms or changes in kidney function to their physician. The dose of Actemra 400 mg should be used with caution in patients with kidney disease. It is important to adjust the dose in patients with kidney disease.
• Breastfeeding: Actemra 400 mg is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
• Liver: Actemra 400 mg Injection should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Actemra 400 mg and report any unusual symptoms or changes in liver function to their doctor. The dose of Actemra 400 Injection may need to be adjusted in patients with liver disease.
• Pregnancy: Actemra Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects on the developing baby; however, there are limited human studies.
• Driving: Actemra 400 mg Injection may cause dizziness, fatigue, and difficulty concentrating and coordinating, which may affect your ability to drive a vehicle safely. It is important to follow your doctor's instructions and take necessary precautions such as avoiding driving a vehicle or operating heavy machinery if you suffer from the side effects of this Actemra 400 mg.

